Apixaban, sold under the brand name Eliquis among others, is an anticoagulant
medication used to treat and prevent blood
clots and to prevent stroke in people with nonvalvular atrial fibrillation.
Apixaban is in a class of medications called factor Xa inhibitors.
It works by blocking the action of a certain natural substance that
helps blood clots to form.
Mechanism of action
ELIQUIS inhibits free and clot-bound factor Xa, and prothrombinase activity.
ELIQUIS has no direct effects on platelet aggregation, but indirectly inhibits platelet aggregation induced by thrombin. By inhibiting
factor Xa, ELIQUIS prevents thrombin generation and thrombus development.
Clears Anticlotting Drug by Bristol and Pfizer. The Food and Drug
Administration on Friday approved Eliquis, an anticlotting drug that
has been highly anticipated by cardiologists and is expected to be a
blockbuster for Bristol-Myers Squibb, which will make the drug, and Pfizer,
which will help market i